Found 27 matching trials
A Dose Ranging Placebo-controlled Double-blind Study to Evaluate the Safety, Pharmacokinetics and Efficacy of 610 in Participants With Severe Eosinophilic Asthma PHASE1 This study will assess the safety, tolerability, pharmacokinetics and preli...
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Shanghai General Hospital
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Real-world Immunogenicity of Anti-IL5/5a Antibody N/A This study aims to evaluate the immunogenicity of the drug by measuring ant...
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Active Not Recruiting
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Samsung Medical Center
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Anti-Interleukin-5 Antibody to Treat Hypereosinophilic Syndrome PHASE2 This study will examine the safety and effectiveness of a single dose of an...
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National Institute of Allergy and Infectious Diseases (NIAID)
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Functional Lung MRI for Early Treatment Response Assessment for Patients With Eosinophilic Asthma N/A Patients with severe eosinophilic asthma will be placed on biologics if the...
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Hannover Medical School
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Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients N/A Real-life, observational, retrospective, multicenter study to evaluate the ...
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Azienda Ospedaliero Universitaria Ferrara
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Comparison of Biologicals in Treatment of Severe Asthma N/A This is a retrospective clinical study on adult patients (18 years or more)...
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Helsinki University Central Hospital
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A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma PHASE2 This study will assess the efficacy and safety of 610 as an adjunctive ther...
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Shanghai General Hospital
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Poor Response to Monoclonal Therapy in Asthma N/A Asthma affects 8% of the entire population. 4-5% of asthma sufferers have s...
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Nottingham Respiratory BRU
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Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection PHASE1 This study is Safety, Tolerability and Pharmacokinetic of Recombinant anti-...
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Shanghai General Hospital
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A Pragmatic Study to Investigate the Efficacy and Safety of Mepolizumab in Severe Uncontrolled Asthma in Brazil PHASE4 The anti-interleukin-5 monoclonal antibody mepolizumab is approved as an ad...
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University of São Paulo
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